Soy isoflavone plus (3/Jan/2008)

Soy isoflavone plus
3/Jan/08

Nanotechnology, an innovative process has been designed in our labs whereby we can mimic the nature and reproduce diatoms skeleton-like. Silicateins have been shown to catalyze the deposition of silica in Vitro, producing nanostructures at ambient temperature and neutral pH. This kind of technique allows us to encapsulate cosmetic active ingredients. In this particular case: isoflavones are our principal ingredient that will be controlled released through nanodiffusion on the skin.

 

Isoflavones (phytoestrogens)
The isoflavones show similar effects than female hormones: Interact with estrogenic receptors the distance between the two hydroxyl groups is the same than the one exists between the two hydroxyl groups in the female hormones.

Antioxidant activity:
Polyphenolic derivatives.
Decrease of the Oxygen free radials

Enzimatic inhibition:
Cellular differentiation.
Inhibition of the metaloproteases resulting from UV radiation.
Increase of collagen synthesis.

Cellular proliferation (fibroblasts)
Increase on the DNA synthesis
The effect is dosage-dependent

Comet Test
Prevention damage of DNA of 100%

ECM protein synthesis

Increase :
Collagen I 100%
Collagen III 110%
Elastin 120%
The effect is dosage-dependent.

Macrorugosity form silicon replica
The average reduction (Ra) is of 24% in 30 days of treatment.